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Korean J Parasitol > Volume 10(1):1972 > Article

Original Article
Korean J Parasitol. 1972 Apr;10(1):22-26. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1972.10.1.22
Copyright © 1972 by The Korean Society for Parasitology
Treatment of hookworm infection with furfurol
Dong Wik Choi,Sung Deok Park,Jae Woun Kim,Chung Hun Choy and Yung Myung Kim
Department of Parasitology, School of Medicine, Kyungpook National University, Taegu, Korea.
Department of Pediatrics, School of Medicine, Kyungpook National University, Taegu, Korea.

Furfurol("Furfudol"), a new anthelmintics, was administered to 7 adults and 21 children (6-12 years old) in total amounts of 15.6 mg(base) for 1 to 3 days. It has proven to be effective against hookworms.

The anthelmintic effect against hookworms with a single dose of 15.6 mg of furfurol was similar to that of a single dose of 2.5 gm of bephenium hydroxynaphthoate. However, when a total of 15.6 mg of the base was given to both children and adult, the side reactions were so mild that the drug can be administered for therapeutic regimens in mass treatment. Minor abdominal discomfort was the only common side effect. This is the primary advantage of furfurol as compared with bephenium hydroxynaphthoate.

These results have indicated that furfurol is safe in therapeutic dosage and is an effective agent to treat patients infected with hookworms.


Table 1
Results of pre-treatment survey of hookworm infections in 21 children and 7 adults

Table 2
Therpeutic efficacy of furfurol against hookworm

Table 3
Side effects observed after the administration of furfurol in 21 children and 7 adults

Table 4
Comparison of therapeutic effects between furfurol and behenium hydroxynaphthoate

1. Choi DW, Park SD, Kim JW, Ahn DH, Kim YM. Intestinal Parasite Survey Of Kyungpook National University Hospital Patients. Korean J Parasitol 1971;9(2):47–53.
2. Harada Y, et al. Medicine and Biology 1951;20:65–67.
3. Ishizaki T, et al. Jpn J Med Sci & Biology 1966;19:239–245.
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