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Korean J Parasitol > Volume 2(3):1964 > Article

Original Article
Korean J Parasitol. 1964 Dec;2(3):175-178. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1964.2.3.175
Copyright © 1964 by The Korean Society for Parasitology
Metabolism of C14-glucose by Eurytrema pancreaticum
Byong Seol Seo,Han Jong Rim,Kwang Soo Kim,Myung Sang Lee,Yeong Uhn Kim and Hi Yong Song
Department of Parasitology and Institute of Endemic Diseases, College of Medicine, Seoul National University, Korea.
Department of Biochemistry, College of Medicine, Seoul National University, Korea.
Abstract

1. The glucose uptake rate by Eurytrema pancreaticum was a mean value of 16.44 ± 2.42 µM/hr/g, and total CO2 production rate by the fluke averaged 5.82 ± 0.97 µM/hr/g. The relative specific activity of respiratory CO2 showed a mean value of 5.75 ± 0.84 per cent. The rate of CO2 production derived from medium C14-glucose was a mean of 0.33 ± 0.10 µM/hr/g. Therefore, the average value of 0.32 ± 0.04 per cent of glucose utilized by the flukes from the medium C14-glucose was oxidized to respiratory CO2.

2. The tissue concentration of glycogen in E. pancreaticum was a mean of 45.50 ± 2.18 mg/g or 4.55 ± 0.22 %/g. But the turnover rate of glycogen pool was a mean of 0.027 ± 0.003 %/hr or 0.009 ± 0.002 mg/hr/g. The average value of 0.64 ± 0.23 percent of glucose utilized by the flukes from the medium C14-glucose was incorporated into the glycogen.

3. These data account for that only 1 per cent of the utilized glucose by the flukes participated in furnishing the oxidation into respiratory CO2 and the synthetic process into glycogen.

Tables


Table 1
The glucose uptake rate and conversion of C14-glucose into respiratory CO2.


Table 2
The tissue concentration of glycogen and conversion of C14-glucose into glycogen.

References
2. VON Brand T. Helminth Abstr 1960;29(2):97–111.
3. Good CA, et al. J Biol Chem 1933;100:485.
4. Lee US. Seoul J Med 1961;2(3):289–295.
5. Nelson N. J Biol Chem 1944;153:375.
6. Rim HJ. Seoul J Med 1963;4(2):51–60.
7. Seo BS, Rim HJ, Kim KS, Rhee SD, Lim SJ, Lee WS. Metabolism Of C(14)-Glucose By Fasciola Hepatica. Korean J Parasitol 1964;2(3):170–174.
 
8. Van Slyke DD, et al. J Biol Chem 1940;136:509.
9. Somogyi N. J Biol Chem 1945;160:61.
10. Stetten D, et al. J Biol Chem 1944;155:231.
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