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Korean J Parasitol > Volume 34(4):1996 > Article

Original Article
Korean J Parasitol. 1996 Dec;34(4):255-258. English.
Published online Dec 20, 1996.  http://dx.doi.org/10.3347/kjp.1996.34.4.255
Copyright © 1996 by The Korean Society for Parasitology
Chronologic change of serum IgG antibody response in chickens reinfected with Cryptosporidium baileyi
Jae Ku Rhee,*Hyeon Cheol Kim and Bae Keun Park
Bio-Safety Research Institute, Chonbuk National University, Chonju 561-756, Korea.
Received September 14, 1996; Accepted November 09, 1996.

Abstract

Eight 2-day-old SPF chickens were each inoculated orally with a single dose of 5×105 oocysts of Cryptosporidium baileyi, and immunoglobulin G (IgG) antibody responses were chronologically measured by indirect immunofluorescent antibody (IFA) assay. Anti-C. baileyi IgG antibody levels remained high(1:106.67 to 1:512.00) for at least 4 months with 330 days of a detectable period. Ten days after the negative conversion, each chicken was re-challenged with 1×107 oocysts of the same species. Subsequent infection in 340-day-old individuals caused sudden elevated IgG antibody levels and the titer peaked on day 28 postchallenge inoculation(PCI), at 1:1,024 with a 65 days of detection period. Chickens in primary infection showed oocyst shedding profiles, but did not exhibit any oocyst shedding before or after experimental reinfection.

Figures


Fig. 1
Serum IgG antibody levels in the primary and secondary antibody responses to Cryprosporidium baileyi in chickens reinfected with oocysts.

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