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Korean J Parasitol > Volume 31(2):1993 > Article

Original Article
Korean J Parasitol. 1993 Jun;31(2):91-97. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1993.31.2.91
Copyright © 1993 by The Korean Society for Parasitology
Experimental infection of Paragonimus westermani in mice and rats
P C Fan,*H Lu and L H Lin
Department of Parasitology, National Yangming Medical College and Parasitology Laboratory, Department of Medical Research, Veterans General Hospital, Taipei, Taiwan, Republic of China.
Received December 21, 1992; Accepted March 15, 1993.


To determine the infectivity and maturity of metacercariae of Paragonimus westermani after keeping at low temperature for a long period, 45 mice and 45 rats were each infected with 20 metacercariae which were kept at 4℃ for 8 to 234 days. The worm recovery in mice increased with age of worm and reached a peak of 32% at 41-50 days and then decreased with age. The rate in rats first decreased to a lowest point of 6% at 71-100 days and then increased with age. In 42 infected mice and 41 infected rats, 187 immature worms (183 tiny and 4 juvenile ones) and 190 worms (164 tiny, 19 juvenile and 7 mature ones) were recovered respectively. Two worm cysts with eggs only and 8 empty worm cysts were also found in the rats. In addition, the frozen metacercariae can still develop to mature worms in SD rats.


Fig. 1
A 123 days old adult worm of P. westermani in a lungcyst of the left upper lobe of a SD rat (Bar = 1 mm).


Table 1
Susceptibility and worm recovery of Paragonimus westermani in rodents

Table 2
Worm recovery rate of Paragonimus westermani in albino mice by age of worms

Table 3
Worm recovery rate of Paragonimus westermani in SD rats by age of worm

Table 4
Comparison of distribution pattern of Paragonimus westermani in albino mice and SD rats

Table 5
Comparison of size of Paragonimus westermani in albino mice and SD rats

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