Prevalence of <i>Enterobius vermicularis</i> infection and preventive effects of mass treatment among children in rural and urban areas, and children in orphanages

, Kim, J S; , Lee, H Y; , Ahn, Y K

doi:1991.29.3.235

Korean J Parasito > Volume 29(3):1991 > Article

Original Article


Korean J Parasitol. 1991 Sep;29(3):235-243. English. Published online Mar 20, 1994. http://dx.doi.org/10.3347/kjp.1991.29.3.235
Copyright © 1991 by The Korean Society for Parasitology


Prevalence of Enterobius vermicularis infection and preventive effects of mass treatment among children in rural and urban areas, and children in orphanages
J S Kim,H Y Lee and Y K Ahn^*
Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju 220-050, Korea.
^*Department of Parasitology, Yonsei University Wonju College of Medicine, Wonju 220-050, Korea.


Abstract
An epidemiological study and mass treatments of Enterobius vermicularis infection among children near Wonju area of Kangwon province were carried out. The children were divided into 4 groups according to their residing localities; children in the mountainous area, rural area, urban area and in orphanage. They were examined by adhesive cellotape anal swab technique, and egg positive rates were obtained. The rates of egg reduction and re-infection rates after repeated mass treatments were also observed. The results obtained were as follows: 1. The overall egg positive rate of E. vermicularis in the first screening was 19.9% (251 out of 1,262 examinees; 19.7% in males and 20.1% in females). The positive rates were 13.0% in the mountainous area, 11.9% in the rural area, 15.1% in the urban (medium-sized) area and 61.9% in orphanages. 2. The highest positive rates were observed in the kindergarten children, and 1st and 2nd grade children of primary schools (26.2-32.2%), and the lowest rate (13.6%) in 6-year grade children of primary schools. 3. Cumulative detection rates from 3 repeated anal swabs at 4-5 days interval were higher (70.8%) than those from single anal swabs (50.0-59.2%). 4. Out of the examinees who showed the highest cumulative positive rate (70.8%), about 39.2% were consecutively positive in 3 anal swabs. Among different groups of children, the higher the total egg detection rates (87.5%), the higher the consecutive positive rates (71.9%). 5. A total of 2,609 (male: female = 1:12.4) worms were collected from 17 egg-positive cases treated with anthelmintics. The mean number of worms per child was 153 (range: 4-824).

Figures


	Fig. 1 Egg detection rate of E. vermicularis by grade of primary school and pertinent age.


	Fig. 2 Changing pattern of egg detection rate after repeated mass treatment in schoolchildren and orphans. Treatment A)~C): Against only egg detected cases at every time(◦), D)~E): Against all subjected children unrelated positive and negative at every time(•)

Tables


	Table 1 Egg detection rates of Enterobius vermicularis by anal swab technique among children nearby Wonju-city area


	Table 2 Comparison of E. vermicularis infection by living environment among children nearby Wonju-city area


	Table 3 Distribution of E. vermicularis infection by grand of class (primary school) and age


	Table 4 Results of repeated examination by anal swab technique for grasp of E. vermicularis infection


	Table 5 Comparison of egg-detected conditions (consecutive and alternative) in infected children by repeated exanimation


	Table 6 Infection intensity of worms by chemotherapy


	Table 7 Evaluation of repeated anthelmintic treatment of E. vermicularis infection in primary school and orphanages


	Table 8 Egg detection rate of brothers or sisters among schoolchildren infected with E. vermicularis

References


1.	Chai JY, Cho SY, Kang SY, Seo BS. Frequency Distribution Of Enterobius Vermicularis In A Highly Endemic Population. Korean J Parasitol 1976;14(2):103–108.

2.	Cherubin CE, Shookhoff HB. The prevalence of enterobiasis, with regard to population group, among 500 children in New York City. Am J Trop Med Hyg 1963;12:69–72.

3.	Cho SY, Kang SY. Significance Of Scotch-tape Anal Swab Technique In Diagnosis Of Enterobius Vermicularis Infection. Korean J Parasitol 1975;13(2):102–114.

4.	Cho SY, Kang SY, Ryang YS, Seo BS. Relationships between the results of repeated anal swab examinations and worm burden of Enterobius vermicularis. Korean J Parasitol 1976;14(2):109–116.

5.	Cho SY, Hong ST, Chai JY, Seo BS. Selection Criteria Of Subjects For Drug Evaluation In Enterobiasis. Korean J Parasitol 1980;18(1):45–53.

6.	Cho SY, Kang SY, Kim SI, Song CY. Effect of anthelmintics on the early stage of Enterobius vermicularis. Korean J Parasitol 1985;23(1):7–17.

7.	Choi WY, Yoo JE, Nam HW, Kim JH, Lee UH. [Egg detection rates of Enterobius vermicularis in children]. Korean J Parasitol 1987;25(2):181–184.

8.	Ho S, Park CB. [Status of Enterobius vermicularis Iifection in primary school children, Yongyang-Kun, Kyongbuk Province]. Korean J Parasitol 1984;22(1):138–140.

9.	Hong ST, Cho SY, Seo BS, Yun CK. Chemotherapeutic control of Enterobius vermicularis infection in orphanages. Korean J Parasitol 1980;18(1):37–44.

*10.*	Saunders LG. A survey of helminth and protozoan incidence in man and dogs at Fort Chipewyan, Alberta. J Parasitol 1949;35(1):31–34.

*11.*	Im KI, Ryu JS, Yong TS, Lee JH, Kim TU. [The egg detection rates of Enterobius vermicularis among school children in the various regions]. Korean J Parasitol 1986;24(2):205–208.

*12.*	Park JY, et al. Kyungpool Univ Med J 1974;15(1):63–67.

*13.*	Ryang YS. Korean J Public Health 1975;12(1):108–114.

*14.*	Ryang YS. [Recent patterns of Enterobius vermicularis infection in some school children, Korea]. Korean J Parasitol 1988;26(3):215–220.

*15.*	Sawitz W, et al. J South Med Assc 1940;33(9):913–922.

*16.*	Seo BS, et al. Seoul J Med 1963;4(1):23–27.

*17.*	Seo BS, Rim HJ, Loh IK, Lee SH, Cho SY, Park SC, Bae JW, Kim JH, Lee JS, Koo BY, Kim KS. [Study On The Status Of Helminthic Infections In Koreans]. Korean J Parasitol 1969;7(1):53–70.