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Korean J Parasitol > Volume 25(2):1987 > Article

Original Article
Korean J Parasitol. 1987 Dec;25(2):149-153. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1987.25.2.149
Copyright © 1987 by The Korean Society for Parasitology
Specific IgG antibody responses in experimental cat metagonimiasis
Seung-Yull Cho,Suk Il Kim and Shin Yong Kang
Department of Parasitology, College fo Medicine, Chung-Ang University, Seoul 151, Korea.
Abstract

In order to observe the feasibility of serologic diagnosis of metagonimiasis, saline extracts of metacercariae and 4-week old adults were prepared. Sera from 25 experimentally infected cats were collected from 3 days to 12 weeks after infection. Their levels of specific IgG antibody were measured by ELISA together with 3 sera from non-infected cats. Specific IgG antibody levels began to rise in 7 days after infection, reached their peak in 2-4 weeks and made a plateau thereafter. Cats infected with hundreds of adult worms showed minimal rise of the antibody level. Adult antigen was superior to metacercarial antigen in detecting the specific IgG antibody.

Figures


Fig. 1
Specific IgG antibody levels in individual cat as measured by ELISA. Open triangle, circle and rectangle (▵, ◦, ▫) mean antibody levels to metacercarial antigen while closed ones (▴, •, ▪) mean those to adult antigen. Triangles (▵,▴): cats infected with less than 1,000, circles (◦, •): cats infected with 1,000~5,000, rectangles (▫, ▪): cats infected with more than 5,000 adults. Markings (◦, ▫) of B (in control cats) represents abs. to metacercarial (◦) or adult (▫) antigens.

Tables


Table 1
Specific IgG antibody levels as measured by ELISA in 25 experimental cats infected with different doses of Metagonimus yokogawai

References
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