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Korean J Parasitol > Volume 12(2):1974 > Article

Original Article
Korean J Parasitol. 1974 Dec;12(2):87-94. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1974.12.2.87
Copyright © 1974 by The Korean Society for Parasitology
Production of DDT-resistance in Bangkok strain of Cheopis fleas under laboratory conditions
Yong Tae Yum
Department of Parasitology, College of Medicine, Chung-Ang University, Korea.
Abstract

Normal Bangkok strain of X. cheopis which had little resistance to DDT in 1966 became moderately resistant in 1972 without any direct exposure to the insecticide. It was analyzed that the causes of resistance gaining were as follows. First, the possibility of being exposed unconsciously to DDT spray under malaria eradication program could not be ruled out, even in laboratory as far as ventilation windows would be open sometime. Insecticides from air spray through the window influenced the fleas kept in the pools. Second, it may be said that initial resistance to DDT has become greater and greater ecologically without any exposure of insecticides. A highly resistant strain of X. cheopis which survived after contacting 4% DDT for five times during one year period was obtained in the laboratory and it showed 100% survival at the highest concentration (4%) of DDT paper by 24 hour exposure. The hybrid forms between normal Bangkok strain and artificially mutated "Resistant Strain" were obtained by mixing the above two colonies. Regardless to the sexes of both ancestors, the results of resistance tests of hybrids showed that artificially gained resistance of fleas to DDT was inherited possibly by recessive hereditary role by pheonotype.

Figures


Fig. 1
Incidence of human plague in Vietnam.


Fig. 2
Mortality of flea after DDT contact for 24 hours (Log dosage mortality probability paper.)

Tables


Table 1
Chronological percentage Mortality of normal Bangkok flea aginst DDT after 24 hour exposure


Table 2
Chronological percentage Mortality of normal Bangkok flea aginst DDT after 1 hour exposure


Table 3
Percentage mortality of resistance gained flea against DDT


Table 4
Percentage mortality of hybrid flea between normal Bangkok flea and "Resistant Flea"

References
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4. Kilpatrick JW. J Econ Ent 1952;45:254–258.
5. Marshall JD, Ouy DV, Gibson FL, Dung TC, Cavanaugh DC. Ecology of plague in Vietnam: commensal rodents and their fleas. Mil Med 1967;132(11):896–903.
 
6. Olson WP. J Econ Ent 1969;66:656–660.
7. Pollitzer R. WHO Monograph Ser 1945;22:315–401.
8. WHO. WHO Tech Rep Ser 1963;264:135–138.
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