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Korean J Parasitol > Volume 4(2):1966 > Article

Original Article
Korean J Parasitol. 1966 Dec;4(2):14-22. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1966.4.2.14
Copyright © 1966 by The Korean Society for Parasitology
Metabolism of C14-glycine by Clonorchis sinensis
Soo Hyun Seong and Byong Seol Seo
Department of Parasitology and Institute of Endemic Diseases, College of Medicine, Seoul National University, Korea.

Radioactive C14-glycine was given to Clonorchis sinensis in Tyrode medium in order to trace the metabolic fate of the labeled carbon. The labeled carbon from glycine enters into every major fraction of Clonorchis sinensis and is highest in the fraction of protein and nucleic acid. Significant amount of C14-glycine is incorporated into respiratory carbon dioxide. Relatively high percentage of C14-glycine in medium is converted to amino acid fraction and lipid fraction of the worm.

In general, glycine is continuously being utilized in the synthesis of proteins and for energy production despite the uptake rate of glycine decreased gradually as incubation proceeds.


Fig. 1
The cumulative curve of C14-glycine which was absorbed by Clonorchis sinensis.

Fig. 2
The uptake rate of glycine and total respiratory CO2 production rate in Clonorchis sinensis.

Fig. 3
The cumulative curves of respiratory CO2 and relative specific activity of C14O2

Fig. 4
Conversion of C14-glycine into four major fractions in Clonorchis sinensis.


Table 1
The glycine uptake rate and conversion of C14-glycine into respiratory CO2

Table 2
Conversion of C14-glycine into four major fractions by Clonorchis sinensis

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