| Home | E-Submission | Sitemap | Contact us |  
Korean J Parasitol > Volume 34(2):1996 > Article

Original Article
Korean J Parasitol. 1996 Jun;34(2):113-119. English.
Published online Jun 20, 1996.  http://dx.doi.org/10.3347/kjp.1996.34.2.113
Copyright © 1996 by The Korean Society for Parasitology
An epidemiological survey of Cryptosporidium parvum infection in randomly selected inhabitants of Seoul and Chollanam-do
J Y Chai,*S H Lee,S M Guk and S H Lee
Department of Parasitology, Seoul National University College of Medicine, Seoul 110-799, Korea.
Received May 07, 1996; Accepted May 27, 1996.


An epidemiological survey was performed to know the status of Cryptosporidium sp. infection among the people in Seoul and Chollanam- do in 1992. One village of Chollanam-do (Hwasun-gun) which showed the highest oocyst positive rate was re-surveyed in 1995 for human infection and for cattle also. The subjected areas consisted of 8 urban villages (= dongs) of Seoul and 4 urban ( = dongs) and 7 rural ( = myons) villages of Chollanam-do. A total of 3,146 fecal samples was collected randomly, and smears were made from formalin-ether sediments. They were examined for Cryptosporidium oocysts by modified acid fast staining. The overall oocyst positive rate was 7.9% (248/3,146), but the rate was remarkably different between Seoul and Chollanam-do, 0.5% (4/853) and 10.6% (244/2,293), respectively. The average size of oocysts was 4.8 ± 0.5 by 4.2 ± 0.5 µm, compatible with C. parvum. In Chollanam-do, rural villages showed significantly higher rate (14.0%) than urban villages (3.7%). Especially the people in Iyang- myon. Hwasun-gun, a typical rural village, revealed a very high rate of 40.0% (74/185). Adults aged 51-70 years revealed the highest positive rate among all age groups. At the re-survey of the same village of Hwasun-gun in 1995, 44 (35.2%) of 125 villagers and 14 (93.3%) of 15 cattle examined were positive for C. parvum oocysts. The results suggest that C. parvum is highly prevalent in rural areas of Chollanam- do, and an important source or mode of infection seems to be contaminated water or contact with the feces of infected cattle.


Fig. 1
Age-prevalence of C. parvum infection among the surveyed population in Seoul and Chollanam-do. 1992.


Table 1
Overall C. parvum oocyst positive rate of the surveyed population

Table 2
C. parvum oocyst positive rate by surveyed areas of Seoul

Table 3
C. parvum oocyst positive rate by urban and rural villages of Chollanam-do

Table 4
Positive rate of C. parvum oocysts according to sex of the people surveyed

Table 5
Second survey results on the prevalence of C. parvum by age of the people in Hwssun-gun layang-myon (April, 1995)

1. Chai JY, Shin SM, Yun CK, Yu JR, Lee SH. [Experimental activation of cryptosporidiosis in mice by immunosuppression]. Korean J Parasitol 1990;28(1):31–37.
2. Cho MH, Kim AK, Im K. Detection of Cryptosporidium oocysts from out-patients of the Severance Hospital, Korea. Korean J Parasitol 1993;31(3):193–199.
3. Current WL, Garcia LS. Cryptosporidiosis. Clin Microbiol Rev 1991;4(3):325–358.
4. D'Antonio RG, Winn RE, Taylor JP, Gustafson TL, Current WL, Rhodes MM, Gary GW Jr, Zajac RA. A waterborne outbreak of cryptosporidiosis in normal hosts. Ann Intern Med 1985;103(6 Pt 1):886–888.
5. Ditrich O, Palkovic L, Sterba J, Prokopic J, Loudova J, Giboda M. The first finding of Cryptosporidium baileyi in man. Parasitol Res 1991;77(1):44–47.
6. Fayer R, et al. Microbiol Rev 1986;50(4):458–483.
7. Garcia LS, et al. J Clin Microbiol 1983;18:185–190.
8. Jokipii L, Pohjola S, Jokipii AM. Cryptosporidium: a frequent finding in patients with gastrointestinal symptoms. Lancet 1983;2(8346):358–361.
9. Kang YK, et al. Seoul J Med 1995;36(1):29–34.
11. Meisel JL, Perera DR, Meligro C, Rubin CE. Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient. Gastroenterology 1976;70(6):1156–1160.
12. Nime FA, Burek JD, Page DL, Holscher MA, Yardley JH. Acute enterocolitis in a human being infected with the protozoan Cryptosporidium. Gastroenterology 1976;70(4):592–598.
13. O'Donoghue PJ. Cryptosporidium and cryptosporidiosis in man and animals. Int J Parasitol 1995;25(2):139–195.
14. Rhee JK, Seu YS, Park BK. [Isolation and identification of Cryptosporidium from various animals in Korea. I. Prevalence of Cryptosporidium in various animals]. Korean J Parasitol 1991;29(2):139–148.
15. Tyzzer EE. Proceed Soc Exp Bio Med 1907;5:12–13.
16. Upton SJ, Current WL. The species of Cryptosporidium (Apicomplexa: Cryptosporidiidae) infecting mammals. J Parasitol 1985;71(5):625–629.
17. Webster KA. Molecular methods for the detection and classification of Cryptosporidium. Parasitol Today 1993;9(7):263–266.
18. Wee SH, Joo HD, Kang YB. Evaluation for detection of Cryptosporidium oocysts in diarrheal feces of calves. Korean J Parasitol 1996;34(2):121–126.
Editorial Office
Department of Molecular Parasitology, Samsung Medical Center, School of Medicine, Sungkyunkwan University,
2066 Seobu-ro, Jangan-gu, Suwon 16419, Gyeonggi-do, Korea.
Tel: +82-31-299-6251   FAX: +82-1-299-6269   E-mail: kjp.editor@gmail.com
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © 2022 by The Korean Society for Parasitology and Tropical Medicine.     Developed in M2PI