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Korean J Parasitol > Volume 27(4):1989 > Article

Original Article
Korean J Parasitol. 1989 Dec;27(4):249-252. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1989.27.4.249
Copyright © 1989 by The Korean Society for Parasitology
Experimental human infection with Fibricola cratera (Trematoda: Neodiplostomidae)
W L Shoop
Merck Institute of Therapeutic Research, Rahway, New Jersey, 07065, USA.

Fibricola cratera is a strigeoid trematode indigenous to North America that, heretofore, was known only to infect wild mammals. Herein, it is reported that an experimental inoculation of a human volunteer produced a patent infection that lasted 40 months. Symptoms of epigastric discomfort, loose stools and flatulence occurred over the first year of infection and ameliorated thereafter. Eggs per gram of stool were low (less than or equal to 2) throughout the course of infection and were not detected by the standard technique of formalin-ether concentration. To monitor infection, the entire stool sample was examined each month after sieving through No. 10 (pore size 2 mm) and 100 (pore size 145 µm) sieves and collecting eggs on a No. 325 (pore size 45 µm) sieve. This is the first report of a North American strigeoid trematode capable of maturing in a human and is only the second species of strigeoid known to do so. The other species is F. seoulensis which has been implicated in 26 human infections in Korea.


Fig. 1
Eggs of Fibricola cratera from the stool of an experimentally-infected human. Eggs measure 70 (65~75) µm wide by 125 (115~135) µm long.


Table 1
Stool data from a human experimentally-infected with 100 metacercariae of Fibricola cratera on 14 March, 1986

2. Cole RA, Shoop WL. Helminths of the raccoon (Procyon lotor) in western Kentucky. J Parasitol 1987;73(4):762–768.
3. Hoffman GL. J Parasitol 1955;41:327.
4. Hong ST, Cho TK, Hong SJ, Chai JY, Lee SH, Seo BS. Fifteen human cases of Fibricola seoulensis infection in Korea. Korean J Parasitol 1984;22(1):61–65.
5. Hong ST, Chai JY, Lee SH. Ten human cases of Fibricola seoulensis infection and mixed one with Stellantchasmus and Metagonimus. Korean J Parasitol 1986;24(1):95–97.
6. Lee SH, Yoo BH, Hong ST, Chai JY, Seo BS, Chi JG. A histopathological study on the intestine of mice and rats experimentally infected by Fibricola Seoulensis. Korean J Parasitol 1985;23(1):58–72.
7. Seo BS, Lee SH, Hong ST, Hong SJ, Kim CY, Lee HY. Studies On Intestinal Trematodes In Korea: V. A Human Case Infected By Fibricola Seoulensis (Trematoda: Diplostomatidae). Korean J Parasitol 1982;20(2):93–99.
8. Seo BS, Lee SH, Chai JY, Hong SJ, Hong ST. The life cycle and larval development of Fibricola seoulensis (Trematoda: Diplostomatidae). Korean J Parasitol 1988;26(3):179–188.
9. Shoop WL, et al. Tulane Studies in Zool Bot 1982;23:109–122.
10. Turner HF. J Alabama Acad Sci 1957;29:43–44.
11. Ulmer MJ. Notes on the morphology and host-parasite specificity of Fibricola cratera (Barker and Noll, 1915) Dubois 1932 (Trematoda: Diplostomatidae). J Parasitol 1955;41(5):460–466.
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