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Korean J Parasitol > Volume 26(2):1988 > Article

Original Article
Korean J Parasitol. 1988 Jun;26(2):121-126. English.
Published online Mar 20, 1994.  http://dx.doi.org/10.3347/kjp.1988.26.2.121
Copyright © 1988 by The Korean Society for Parasitology
Efficacy of praziquantel (CesocideCesocide® injection) in treatment of cestode infections in domestic and laboratory animals
Kee Seon Eom,Seung Ho Kim,* and Han Jong Rim**
Department of Parasitology,College of Medicine, Chungbuk National University, Cheonju 360-763, Korea.
*Department of Animal Husbandry, College of Agriculture, Cheju University, Cheju 690-121, Korea.
**Department of Parasitology, College of Medicine, Korea University, Seoul 110-522, Korea.

Efficacy of praziquantel (Cesocide injection) by intramuscular (I.M.) route against cestode infections was evaluated. Total 93 domestic or laboratory animals such as dogs, cats, rats, mice, goats, deers and chickens were used. Animals were infected with Dipylidium caninum, Spirometra sp., Taenia pisiformis, Taenia taeniaeformis, Hymenolepis nana, Moniezia expansa, Moniezia sp. or Raillietina sp. A single dose of praziquantel, 6 mg/kg of body weight, was highly effective (97.9%) against cestodes of various kinds disregarding the host species or their intensity of infection. At high dose above 6 mg/kg, the cure rate was 100%. All the cestodes treated were expelled from the host within 48 hours. The discharged proglottids were damaged severely except Hymenolepis nana and Moniezia expansa. Intramuscular injection of this drug evoked a brief pain response in a dog, but no other side reactions were observed.


Table 1
Efficacy of praziquantel injection for treatment of cestode infections in animals

Table 2
Expulsion of proglottides after injection of praziquantel

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Praziquantel(Distocide®) in treatment of Clonorchis sinensis infection  1983 December;21(2)
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